Saturday, January 31, 2009

Allicin makes Antibiotics work better!

There is a report published in The Journal of Antibiotics (April 2007) that claims that Allicin is synergistic with Antibiotics.

Abstract Allicin is one of the most effective compounds isolated from garlic showing antibacterial activity. Determination of MIC alone or in combination with cefazolin/oxacillin against Staphylococcus spp. or with cefoperazone against Pseudomonas aeruginosa showed that allicin alone did not have good antibacterial activity (MIC90 >512 μg/ml) but it facilitated antibacterial activity of all three β-lactams tested at subinhibitory concentrations. In the presence of 1/8 to 1/2 the MIC of allicin, the MIC90 values of cefazolin, oxicillin, and cefoperazone were reduced by 4~128, 32~64, and 8~16 fold, respectively. Thus, allicin-β-lactam combinations offer promise of clinical utility especially if synergism is demonstrated by in vivo experimental studies.
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Friday, January 30, 2009

Hypochlorite solutions may be useful in managing CA-MRSA

A recent research report (December 2008) indicates that Bleach Baths may be useful in managing CA-MRSA outbreaks.
The researchers suggest that a five-minute soak in a bleach solution consisting of 2.5 mcL of bleach diluted into 13 gallons of water, or about one-half cup of bleach diluted into a 50-gallon standard tub filled one-quarter with water, could decrease CA-MRSA colonies by more than 99.9%.
Click here for the full article.